Vicryl polyglactin 910 is a copolymer of 90% Glycolide and 10% L-lactide. Following absorption polyglactin 910 is metabolized entirely by hydrolysis to glycolic and lactic acids, which are normal metabolites in the body. Vicryl polyglactin 910 synthetic absorbable surgical sutures are available in undyed (clear) and colored (dyed) forms. The undyed form is indicated for use where tissue reactivity is of concern, such as in ophthalmic and neurosurgical procedures, cardiovascular surgery, microsurgery, and pediatric surgery. The dyed form is available in blue, violet, and black for easy visibility during handling and placement.
Vicryl Polyglactin 910 Synthetic Absorbable Suture Is A Copolymer Of 90% Glycolide, And 10% L-Lactide
- Vicryl polyglactin 910 is a copolymer of 90% Glycolide and 10% L-lactide. It is a synthetic absorbable suture made from polyglycolic acid. The glycolide part of the material can be found in other sutures such as Ethibond or Vicryl Suture M5, which are both made from polyglycolic acid but with different modifications to make them more suitable for use in human tissue repair procedures.
- Glycolides have been used for some time as fillers for soft tissues as they have high water content making them ideal for use during surgical procedures that require quick reabsorption after implantation (such as bone grafts). However, because they are not biocompatible like collagen or gelatinous fibers, they do not last long once implanted into the body – typically only 2 months before being absorbed by natural processes inside the body, which causes problems when trying to treat conditions such as arthritis where joints become inflamed due to inflammation caused by chronic pain caused by overuse/misfiring of muscles.
Following Absorption Polyglactin 910 Is Metabolized Entirely by Hydrolysis
Following absorption, polyglactin 910 is metabolized entirely by hydrolysis to glycolic and lactic acids, which are normal metabolites in the body. These two types of acids are released by the body into systemic circulation at a low rate (about 4% of total absorbed). Still, they can be detected in urine samples at higher levels during long-term exposure or high doses of antidiabetic drugs containing sulfonylurea compounds (e.g., chlorpropamide).
Glycolic acid has been reported to have anti-inflammatory effects on human skin cells in vitro; this mechanism may explain its use as an ingredient in topical creams for eczema treatment.
Vicryl Polyglactin 910 Has A Monofilament Structure
Vicryl Polyglactin 910 has a monofilament structure, giving it a smooth surface that reduces friction against tissue, minimizes trauma to the tissue, and allows for easy passage through tissue. The monofilament polyglycolide backbone is combined with the L-lactide crosslinker, which gives Vicryl polyglycolide 910 its unique properties, such as high tensile strength and resistance to wear. This ensures that even after repeated passages through an animal’s body, there will be no damage caused by motion or compression of the suture material itself.
The Absence of Foreign Body Reaction Minimizes Inflammation and Tissue Reaction
Vicryl polyglactin 910 is an absorbable suture material ideal for use in ophthalmic, cardiovascular, and pediatric procedures. The absence of foreign body reaction minimizes inflammation and tissue reaction.
Vicryl has been shown to reduce the risk of infection compared to other types of sutures, including silk or nylon products. It’s also an ideal material for closing wounds since it does not require heat sealing or adhesive sealing agents like other materials might require during surgery.
In addition to being gentle on the patient’s eye, Vicryl Polyglactin 910 also contains more than 5% cross-linked fibrin protein that promotes wound healing by promoting angiogenesis.